pentobarbital will decrease the extent or effect of aripiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will decrease the level or result of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of abemaciclib with solid CYP3A4 inducer